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Psoriasis Beschreibung

Find information Psoriasis Beschreibung medical topics, symptoms, drugs, procedures, news and more, written for the health care professional. Psoriasis is an Psoriasis Beschreibung disease that manifests most commonly as well-circumscribed, erythematous papules and plaques covered with silvery scales.

Multiple factors contribute, Psoriasis Beschreibung genetics. Common triggers include trauma, infection, and certain drugs. Symptoms are usually minimal, Psoriasis Beschreibung mild to severe itching Psoriasis Beschreibung occur. Cosmetic implications may be major. Some people develop severe disease with painful arthritis. Diagnosis is based on appearance and distribution of lesions. Treatment can include topical treatments eg, emollients, vitamin D analogs, retinoids, coal tar, anthralin Psoriasis Beschreibung, corticosteroidsphototherapy, and, when severe, systemic drugs eg, methotrexatePsoriasis Beschreibung retinoids, cyclosporineimmunomodulatory agents [biologics].

Psoriasis is hyperproliferation of epidermal keratinocytes combined with inflammation of the epidermis and dermis. Peak onset is roughly bimodal, most often at ages 16 to Psoriasis Beschreibung and at ages 57 to 60, but the disorder can Psoriasis Beschreibung at any age. The cause of psoriasis is unclear but involves immune stimulation of epidermal keratinocytes; T Psoriasis Beschreibung seem to play a Psoriasis Beschreibung role.

Genomewide linkage analysis has Psoriasis Beschreibung numerous psoriasis susceptibility loci; the PSORS1 locus on chromosome 6p21 plays the greatest role in determining a patient's susceptibility of developing psoriasis.

An environmental trigger is thought Psoriasis Beschreibung evoke an inflammatory response and subsequent hyperproliferation of keratinocytes. Drugs especially beta-blockers, chloroquinelithiumACE inhibitors, indomethacinterbinafineand interferon-alfa.

Lesions are either asymptomatic or pruritic and are most often localized on the Psoriasis Beschreibung, extensor surfaces of the elbows and knees, sacrum, buttocks commonly the gluteal cleftand genitals. The nails, eyebrows, axillae, umbilicus, and perianal region may also be affected. The disease can be widespread, involving confluent areas of skin extending between these Psoriasis Beschreibung. Lesions differ in appearance depending on type.

Lesions appear gradually and remit Psoriasis Beschreibung recur spontaneously or with the appearance and resolution of triggers. Besides the patient's appearance, the sheer amount of time required to treat extensive skin or scalp lesions and to maintain clothing and bedding may adversely affect quality of life. Gradual appearance of discrete, erythematous papules or plaques covered with thick, Psoriasis Beschreibung, shiny scales.

Topical corticosteroids of Psoriasis Beschreibung effective potency, with or without vitamin D 3 visit web page eg, calcipotriol. Systemic immunosuppressant or immunomodulatory drugs eg, methotrexatecyclosporineTNF-alpha inhibitor. Psoriasis Psoriasis Beschreibung intertriginous areas usually the inguinal, gluteal, axillary, inframammary, and retroauricular folds and the glans of the uncircumcised penis.

Abrupt appearance of multiple plaques 0. Systemic retinoids, topical corticosteroids, vitamin D 3 analogs eg, calcipotriolsystemic immunosuppressant or immunomodulatory drugs eg methotrexate Psoriasis Beschreibung, cyclosporine Psoriasis Beschreibung, TNF-alpha inhibitor.

Pitting, stippling, fraying, discoloration oil spot signand thickening of the nails, with or without separation of the nail plate onycholysis. Systemic retinoids, vitamin D 3 analogs eg, calcipotrioltopical corticosteroids. Systemic retinoids or methotrexate. Gradual or sudden onset of diffuse erythema, usually in patients with plaque psoriasis link the first manifestation of erythrodermic psoriasis ; typical psoriatic plaques less prominent or absent.

Most commonly triggered by inappropriate use of topical or systemic corticosteroids or Psoriasis Beschreibung therapy. Potent systemic drugs eg, methotrexatecyclosporineTNF-alpha inhibitor or intense topical therapy, sometimes as inpatient therapy.

Tars, anthralinand phototherapy likely to exacerbate the condition. Dermatophytoses potassium hydroxide wet mount should be done for any scaly plaques, especially if they do Psoriasis Beschreibung have a classic appearance of eczema or psoriasis. Squamous cell carcinoma in situ Bowen Psoriasis BeschreibungPsoriasis Beschreibung when on the trunk; this diagnosis should be Psoriasis Beschreibung for isolated plaques that do not respond to usual therapy.

Biopsy is rarely necessary and may not be diagnostic; however, it may be considered in cases where the clinical findings are not classic. Disease is graded as mild, moderate, or Behandlung von Nagelplatten in psoriasis based Arthritis Behandlung von Psoriasis the body surface area affected and how the lesions affect the patient's Psoriasis Beschreibung of life.

To be considered mild, usually Psoriasis Area and Severity Indexbut these systems are useful mainly in research protocols. Treatment options are extensive Psoriasis Beschreibung range from topical treatments eg, emollients, salicylic acid, coal tar, anthralincorticosteroids, vitamin D 3 source, calcineurin inhibitors, tazarotene to UV light therapy to systemic treatments eg, methotrexateoral retinoids, cyclosporinebei Jod Psoriasis hilft agents [biologics].

See the American Academy Psoriasis Beschreibung Dermatology's clinical guideline for psoriasis. Corticosteroids are usually used topically but may be injected into small or recalcitrant lesions. Systemic corticosteroids may precipitate exacerbations or development of pustular psoriasis and should not be used to treat psoriasis.

Topical corticosteroids are used twice daily. Corticosteroids are most effective when used overnight under occlusive polyethylene coverings or incorporated into tape; a corticosteroid cream is applied without occlusion during the day. Corticosteroid potency is selected according to the extent of involvement. As lesions abate, the corticosteroid should be applied less frequently or at a lower potency to minimize local atrophy, striae formation, and telangiectases. Ideally, after about 3 wk, an emollient should be substituted Psoriasis Beschreibung the corticosteroid for 1 to 2 wk as a rest period ; this substitution limits corticosteroid dosage and prevents tachyphylaxis.

Topical corticosteroid use can be expensive because large quantities about 1 oz click the following article 30 g are needed Psoriasis Beschreibung each Psoriasis Beschreibung when a large body surface area is affected.

Psoriasis Beschreibung corticosteroids applied for long duration to large areas of the body may cause systemic effects and Psoriasis Beschreibung psoriasis. For small, Psoriasis Beschreibung, localized, or recalcitrant lesions, high-potency corticosteroids are used with an occlusive dressing or flurandrenolide tape; these dressings Psoriasis Beschreibung left on overnight and changed in the morning. Relapse after topical corticosteroids are stopped is often faster Psoriasis Beschreibung with other agents.

Vitamin D 3 analogs eg, calcipotriol [ calcipotriene ], calcitriol are topical vitamin D analogs that induce normal keratinocyte proliferation and differentiation; they can be used alone or in combination with topical corticosteroids. Some clinicians have patients apply calcipotriol on weekdays Psoriasis Beschreibung corticosteroids on weekends. Psoriasis Beschreibung inhibitors eg, tacrolimuspimecrolimus are available in topical form and are generally well-tolerated.

They are not as effective Psoriasis Beschreibung corticosteroids but may avoid the complications Psoriasis Beschreibung corticosteroids when treating facial and intertriginous psoriasis. It is not clear whether they increase the risk of Psoriasis Beschreibung and skin cancer. Tazarotene is a topical retinoid. It is less effective than corticosteroids as monotherapy but is a useful adjunct. Other adjunctive topical treatments include emollients, salicylic acid, coal tar, and anthralin.

Emollients include emollient creams, ointments, petrolatum, paraffin, and even hydrogenated vegetable cooking Psoriasis Beschreibung. They reduce scaling and are most effective when applied twice Psoriasis Beschreibung and immediately after bathing.

Lesions may appear redder as scaling decreases Psoriasis Beschreibung becomes more transparent. Emollients are safe and should probably always be used for mild to moderate plaque psoriasis.

Salicylic acid is a keratolytic that softens scales, facilitates Psoriasis Beschreibung removal, and increases Psoriasis jugendliche Fotos of other topical agents. It is especially useful as a component of scalp treatments; scalp scale can be quite thick. Coal tar preparations are anti-inflammatory and decrease keratinocyte hyperproliferation via an unknown mechanism. Ointments or solutions are Psoriasis Beschreibung applied at night and washed off in the morning.

Coal tar products can be used in combination with Psoriasis Beschreibung corticosteroids or with exposure to natural or artificial broad-band UVB light to Psoriasis Beschreibung in slowly increasing increments Goeckerman Psoriasis Beschreibung. Shampoos should be left in for 5 to 10 min and then rinsed out.

Anthralin is a topical antiproliferative, anti-inflammatory agent. Its mechanism of action is unknown. Effective dose is 0. Anthralin may be irritating and should be used with caution in intertriginous areas; it also stains.

Irritation and staining can Psoriasis Beschreibung avoided by washing off the anthralin 20 to 30 min after application. Using a liposome-encapsulated preparation may also avoid some disadvantages of anthralin. UV light therapy is typically Psoriasis Beschreibung in patients with extensive psoriasis.

The mechanism of action is unknown, although UVB light reduces DNA synthesis and can induce mild systemic immunosuppression. PUVA has an antiproliferative effect and also helps to normalize keratinocyte differentiation.

Doses of light are started low and increased as tolerated. Severe burns can result if the dose of drug or UVA is too high. Although the Psoriasis Beschreibung is less messy than topical treatment and Psoriasis Beschreibung produce remissions lasting several months, repeated treatments may increase the incidence of UV-induced skin cancer and melanoma.

Excimer laser therapy is a type of Psoriasis Beschreibung using a nm laser directed at focal psoriatic plaques. Methotrexate taken orally is an effective treatment for severe disabling psoriasis, especially severe psoriatic arthritis or widespread erythrodermic or pustular psoriasis unresponsive to topical agents or UV light therapy narrowband UVB [NBUVB] or psoralen plus ultraviolet A Http://mgv-frohsinn1904.de/jujyxobyda/behandlung-von-psoriasis-in-der.php. Methotrexate seems to interfere with the rapid proliferation of epidermal cells.

Psoriasis Beschreibung, renal, and hepatic function should be monitored. Dosage regimens vary, so only physicians experienced in its use for check this out should undertake methotrexate therapy. Systemic retinoids eg, acitretin Hypothyreose und juckende, isotretinoin may be effective for severe and recalcitrant cases of psoriasis vulgaris, pustular psoriasis in which isotretinoin may be preferredand hyperkeratotic palmoplantar psoriasis.

Because of the teratogenic potential Psoriasis Beschreibung long-term retention of acitretin in the body, women who use it must not be pregnant and should be warned against becoming pregnant for at least 2 yr after treatment ends. Pregnancy restrictions also apply to isotretinoinbut the agent is not retained in the body beyond Psoriasis Beschreibung mo.

Long-term treatment may cause diffuse idiopathic skeletal hyperostosis DISH. Immunosuppressants can Psoriasis Beschreibung used Psoriasis Beschreibung severe psoriasis. Cyclosporine is a commonly used immunosuppressant. It should be limited to courses of several months Psoriasis Beschreibung, up to 1 yr and alternated with other therapies. Its effect on the kidneys and potential long-term effects on the immune system preclude more liberal use.

Other immunosuppressants eg, hydroxyurea6- thioguaninemycophenolate mofetil have narrow Psoriasis Beschreibung margins and are reserved for severe, recalcitrant psoriasis.

Immunomodulatory agents biologics—see Immunotherapeutics include TNF-alpha inhibitors etanerceptadalimumabinfliximab. TNF-alpha inhibitors lead to clearing of psoriasis, but their safety profile is still under just click for source. Efalizumab is no longer available in the US due to increased risk of progressive multifocal leukoencephalopathy.

Psoriasis Beschreibung

Die Schuppenflechte Psoriasis ist click the following article häufig auftretende, chronisch-entzündliche, gutartige und immer wiederkehrende Hauterkrankung, bei der eine Psoriasis Beschreibung Schuppenbildung Psoriasis Beschreibung. Die Schuppenflechte ist nicht ansteckend; sie kann vererbt werden.

Die Schuppenflechte Psoriasis ist eine nicht ansteckende, familiär gehäuft auftretende chronische Hautkrankheit. Die Phase Psoriasis Beschreibung Hauterneuerung verkürzt sich beim Psoriatiker von 26 auf sechs source sieben Tage und lässt so die Haut schneller nachwachsen, was die typischen Verdickungen an den betroffenen Stellen entstehen lässt.

Die Schuppenbildung entsteht durch die ebenfalls verkürzte Phase Psoriasis Beschreibung Psoriasis bicarb der Haut. Nach derzeitigem medizinischen Erkenntnisstand wird Psoriasis Beschreibung ausgegangen, dass ein genetisch bedingter Defekt im Zusammenspiel mit verschiedenen Umwelteinflüssen das Auslösen der Erkrankung bewirkt.

Article source 3 Prozent der Bevölkerung in Mitteleuropa ist von dieser schubartig auftretenden Krankheit betroffen. Eine vollständige Heilung der Schuppenflechte ist bisher nicht möglich.

Zudem können auch durch eine. Das ohnehin phasenhafte Auftreten der Krankheitssymptome sowie individuelle psychologische Einflussfaktoren erschweren jedoch bei allen Behandlungsansätzen eine generelle Psoriasis Beschreibung über ihre Wirksamkeit.

Paradisi-Redaktion - Artikel vom Ziel ist es, die Fähigkeiten des Abwehrsystems entweder Psoriasis Beschreibung steigern oder wiederherzustellen. Cookies erleichtern Psoriasis Beschreibung Bereitstellung unserer Dienste. Durch die Nutzung unserer Website erklären Sie sich damit einverstanden, dass wir Cookies setzen. Psoriasis Beschreibung erfahren Sie mehr OK. Dermatika - Anwendung, Wirkung und Nebenwirkungen Hautausschlag: Neuer Wirkstoff könnte erstmals die Heilung möglich click Schuppenflechte im Genitalbereich: Studie macht Hoffnung 1 2 Mehr News.

Click Informationen zum Thema Schuppenflechte. Übersicht Artikel News Forum. Scheidenpilz Woher der unangenehme Pilz kommt und wie man ihn wieder los wird.

Lokale Therapien von Psorias

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